Klotho

Also known as: β-Klotho, Klotho-related protein, α-Klotho, KL, Klotho-FGF23 receptor, Klotho alpha, KL1, Klotho gene, Klotho beta

Klotho is a protein that has garnered significant attention in the fields of aging and cognitive health due to its potential role in promoting longevity and enhancing brain function. Named after the Greek goddess of fate, Klotho was first identified in mice in the late 1990s, where it was observed that a deficiency in this protein led to symptoms resembling accelerated aging, such as arteriosclerosis, osteoporosis, and cognitive decline. In humans, Klotho is primarily produced in the kidneys and brain, and it functions as both a circulating hormone and a membrane-bound co-receptor. Its primary...

Potential Side Effects

Side effects score: 1; Klotho is a supplement that is being studied for its potential anti-aging and cognitive benefits, but it's important to be aware of possible side effects. As of now, there is limited research on the supplement, so the full range of side effects is not completely understood. However, some users have reported mild side effects such as headaches, dizziness, and gastrointestinal