3D ball-and-stick molecular model of Pregnenolone on a white background, the "mother hormone" precursor.

Pregnenolone

Also known as: Pregnenolone sulfate, 3β-Hydroxypregn-5-en-20-one, 5-Pregnen-3β-ol-20-one, Pregn-5-en-3-ol-20-one, DHEA precursor, Pregnenolone acetate

Pregnenolone is a naturally occurring hormone produced in the body, primarily within the adrenal glands. It acts as a precursor for various other hormones essential for managing stress responses, mood regulation, and sustaining overall energy levels. As people age, the levels of pregnenolone can decrease, often resulting in symptoms such as fatigue, memory problems, or mood fluctuations. To counteract these effects, some individuals turn to pregnenolone supplements with the aim of boosting their hormone levels, thereby improving their energy, focus, and emotional well-being. When taken as a s...

Potential Side Effects

Side effects score: 3; Pregnenolone may cause side effects including headaches, dizziness, irritability, fatigue, and mood changes. It can also lead to hormonal imbalances and may interact with medications that affect hormone levels.

Health Categories

View efficacy ratings for Pregnenolone across multiple health categories.

Research & Evidence

Our efficacy ratings are based on scientific research and clinical studies.

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