NSI-189 supplement

NSI-189

Also known as: NSI-189 phosphate, NSI-189, NSI-189 freebase

NSI-189 is an experimental compound that has garnered interest for its potential cognitive and mood-enhancing effects. Originally developed by Neuralstem, Inc., this compound is a derivative of nicotinamide and pyrazine, and it was initially investigated for its potential to treat major depressive disorder (MDD). The compound operates by stimulating neurogenesis, which is the process of forming new neurons in the brain, particularly in the hippocampus—a region associated with memory, learning, and mood regulation. The ability to promote neurogenesis suggests that NSI-189 might help in repairin...

Potential Side Effects

Side effects score: 3; NSI-189 is an experimental supplement that has been studied primarily for its potential effects on depression and cognitive function. Some reported side effects include headaches, dizziness, and fatigue. There have also been reports of increased anxiety and irritability in some users. Additionally, some individuals have experienced gastrointestinal issues such as nausea and

Health Categories

View efficacy ratings for NSI-189 across multiple health categories.

Research & Evidence

Our efficacy ratings are based on scientific research and clinical studies.

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