
Letrozole
Also known as: Femara, CGS 20267, 4-(1H-1,2,4-Triazol-1-yl)-1,2,3-phenyl-1-butan-2-ol
Letrozole is a medication primarily used to treat certain types of breast cancer, especially in postmenopausal women. This drug is part of a class known as aromatase inhibitors, which function by obstructing the enzyme aromatase. Aromatase plays a crucial role in the conversion of androgens (male hormones) into estrogens (female hormones) within the body. Many breast cancers rely on estrogen to grow, so by reducing estrogen levels, letrozole helps to slow or stop the growth of these hormone-sensitive cancer cells. In simple terms, letrozole serves to significantly lower the amount of estrogen,...
Potential Side Effects
Side effects score: 6; Letrozole, a medication commonly used for treating hormone receptor-positive breast cancer, may cause side effects such as hot flashes, joint pain, fatigue, and nausea. It can also increase the risk of developing osteoporosis and may lead to mood changes and cardiovascular issues.
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Research & Evidence
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