3D ball-and-stick molecular model of Alpha-ketoglutarate (AKG) used for metabolic health and cellular longevity.

Alpha-ketoglutarate

Also known as: Alpha-ketoglutaric acid, 2-ketoglutarate, AKG, α-Ketoglutarate, 2-oxoglutarate, L-alpha-ketoglutarate

Alpha-ketoglutarate (AKG) is an essential compound with significant functions in energy production and metabolism, naturally present within the mitochondria of cells—often referred to as the powerhouses of cells. Central to the Krebs cycle, AKG facilitates the conversion of nutrients into energy, emphasizing its vital role in cellular processes. As a dietary supplement, AKG is increasingly popular among athletes and fitness enthusiasts, attributed to its purported benefits in supporting muscle health, enhancing exercise performance, and aiding in post-workout recovery. By promoting efficient p...

Potential Side Effects

Side effects score: 2; Alpha-ketoglutarate is generally considered safe for most people, but potential side effects may include gastrointestinal discomfort, nausea, diarrhea, and headache. Although rare, more serious side effects such as metabolic disturbances could occur, particularly in individuals with pre-existing medical conditions.

Health Categories

View efficacy ratings for Alpha-ketoglutarate across multiple health categories.

Research & Evidence

Our efficacy ratings are based on scientific research and clinical studies.

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