Molecular structure model of Adrafinil on a white background, a synthetic compound used for alertness and focus.

Adrafinil

Also known as: Orgaram, CRL-40028, Adrafinil sulfate, 2-((diphenylmethyl)thio)-N-hydroxyacetamide

Adrafinil is a supplement commonly used to enhance focus, alertness, and energy levels. Originally developed as a medication in France during the late 1970s, it was designed to aid individuals with sleep disorders, particularly those struggling to stay awake. The way adrafinil functions is by stimulating certain brain regions, thereby increasing wakefulness and reducing the sensation of fatigue. Upon ingestion, adrafinil is metabolized in the liver into modafinil, a compound known for its robust ability to enhance mental performance and maintain wakefulness, making it popular among people need...

Potential Side Effects

Side effects score: 6; Adrafinil, a supplement used to promote wakefulness, commonly causes side effects such as insomnia, headaches, gastrointestinal issues, nervousness, and an increased heart rate. In rare cases, it can lead to liver toxicity, allergic reactions, and agitation. Users should be aware of these potential effects and monitor their health accordingly.

Health Categories

View efficacy ratings for Adrafinil across multiple health categories.

Research & Evidence

Our efficacy ratings are based on scientific research and clinical studies.

Related Supplements

Supplements commonly explored alongside Adrafinil

Alpha-GPC
Alpha-GPC
Caffeine
Caffeine
Modafinil
Modafinil
Acetyl-L-Carnitine
Acetyl-L-Carnitine
L-theanine
L-theanine